Drug Enforcement Administration (DEA) published a guidance document regarding “suspicious orders” of controlled substances (CS). The document clarifies that neither DEA nor the Controlled Substances Act have regulations that dictate quantitative thresholds or place limits on the volume of CS that DEA-registered manufacturers or distributors can order and dispense. Instead, to comply with statutory and regulatory requirements that manufacturers and distributors monitor and report to DEA any suspicious orders, many DEA-registered manufacturers and distributors establish CS monitoring systems that set thresholds that may limit the number of a customer’s CS purchases and may prompt a report of a suspicious order to DEA. More details are available on the DEA website.