The North American Pharmacist Licensure Examination® (NAPLEX®) Competency Statements provide a blueprint of the topics covered on the examination. They offer important information about the knowledge, judgment, and skills you are expected to demonstrate as an entry-level pharmacist. A strong understanding of the Competency Statements will aid in your preparation to take the examination.

Area 1 – Ensure Safe and Effective Pharmacotherapy and Health Outcomes (Approximately 67% of Test)

1.1 – Obtain, Interpret, Assess, and/or Evaluate:

  • 1.1.1 – Information from patient interviews
  • 1.1.2 – Patient medical records
  • 1.1.3 – Results from instruments and screening strategies used to assess patients
  • 1.1.4 – Laboratory and diagnostic findings
  • 1.1.5 – Signs and symptoms associated with diseases and medical conditions
  • 1.1.6 – Patients’ need for medical referral
  • 1.1.7 – Risk factors relevant to the prevention of a disease or medical condition and the maintenance of wellness
  • 1.1.8 – Information from interdisciplinary health care providers

1.2 – Develop and Implement Individualized Treatment Plans, Taking Into Consideration:

  • 1.2.1 – Specific uses and indications and dosing for drugs
  • 1.2.2 – Purported uses and indications for dietary supplements and complementary and alternative medicine
  • 1.2.3 – Lifestyle and self-care therapy
  • 1.2.4 – Pharmacologic classes and characteristics of drugs
  • 1.2.5 – Actions and mechanisms of actions of drugs
  • 1.2.6 – The presence of pharmacotherapeutic duplications and/or omissions
  • 1.2.7 – Drug interactions
  • 1.2.8 – Contraindications, warnings, and precautions
  • 1.2.9 – Allergies
  • 1.2.10 – Adverse effects and drug-induced illness
  • 1.2.11 – Pharmacodynamic, pharmacokinetic, and pharmacogenomic principles
  • 1.2.12 – Pharmacokinetic data to determine equivalence among drug products
  • 1.2.13 – Pharmacoeconomic factors
  • 1.2.14 – Routes and methods of administration, dosage forms, and delivery systems

1.3 – Assess and Modify Individualized Treatment Plans, Considering:

  • 1.3.1 – Therapeutic goals and outcomes
  • 1.3.2 – Safety of therapy
  • 1.3.3 – Efficacy of therapy
  • 1.3.4 – Medication non-adherence or misuse

1.4 – Techniques for Effective Communication/Documentation of the Development, Implementation, and Assessment of Individualized Treatment Plans to:

  • 1.4.1 – Patients and/or patients’ agents
  • 1.4.2 – Interdisciplinary health care providers

1.5 – Advocate Individual and Population-Based Health and Safety, Considering:

  • 1.5.1 – Best practices, scientific literature evaluation, and health-related resources
  • 1.5.2 – Quality improvement strategies in medication-use systems
  • 1.5.3 – Processes, evaluation of, and responses regarding medication errors
  • 1.5.4 – Role of automated systems and technology in medication distribution processes
  • 1.5.5 – Emergency preparedness protocols

Area 2 – Safe and Accurate Preparation, Compounding, Dispensing, and Administration of Medications and Provision of Health Care Products (Approximately 33% of Test)

2.1 – Employ Various Techniques to Calculate:

  • 2.1.1 – Patients’ nutritional needs and the content of nutrient sources
  • 2.1.2 – Drug concentrations, ratio strengths, and/or extent of ionization
  • 2.1.3 – Quantities of medication to be compounded, dispensed, or administered
  • 2.1.4 – Quantities of ingredients needed to compound preparations
  • 2.1.5 – Rates of administration

2.2 – Compound Sterile and Nonsterile Products, Considering:

  • 2.2.1 – Techniques, procedures, and equipment for drug preparation, compounding, and administration of sterile products
  • 2.2.2 – Techniques, procedures, and equipment for drug preparation, compounding, and administration of nonsterile products
  • 2.2.3 – Physicochemical properties of active and inactive ingredients
  • 2.2.4 – Identifying the presence of, and the cause of, product incompatibilities or degradation and methods for achieving stability
  • 2.2.5 – Physiochemical properties of drugs that affect solubility and stability

2.3 – Review, Dispense, and Administer Drugs and Drug Products, Considering:

  • 2.3.1 – Packaging, labeling, storage, handling, and disposal of medications
  • 2.3.2 – Commercial availability, identification, and ingredients of prescription and non-prescription drugs
  • 2.3.3 – Physical attributes of drug products
  • 2.3.4 – Specific instructions and techniques for administration